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VUGENE multi-omics platform

Learn how multi-omics data analysis and interpretation software can transform raw data into actionable scientific insights.

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multi-omics
Publication
June 1, 2026

Multi-omic Analysis Reveals Ciliogenesis as a Novel Modulator of Parkinson’s Disease Progression

Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting dopamine-producing neurons in the substantia nigra. At its core, PD is driven by the accumulation and spread of α-synuclein (αSyn) into ...

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brain injury
Publication
March 5, 2026

The Molecular Architecture of Severe Pediatric Traumatic Brain Injury: A Multi-Omic Longitudinal Study

Traumatic brain injury (TBI) remains a leading cause of death and long-term disability in children worldwide (Dewan et al., 2016). Despite its impact, clinical management is still largely limited to ...

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transcriptomics
Data analysis
November 18, 2025

Transcriptomics

Transcriptomics (or more specifically RNA-seq) is one of the most dynamic processes in biology where thousands of RNAs are transcribed and degraded every minute. While RNA takes many different forms ...

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mouse
Publication
October 29, 2025

The Impact of an Experimental Senolytic Drug on Muscle Injury in Young and Old Mice – Multi-omics Insights and Changes in DNA Methylation Age

The presence of senescent cells is commonly viewed as a hallmark of aging, as is an increase in cellular DNA methylation age (DNAmAGE). In a recent study, researchers looked at ...

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Juozas Gordevicius
Data analysis
September 9, 2025

VUGENE – New Approaches For “Getting Data to Confess”

Juozas Gordevičius, CTO and Founder of VUGENE Over recent decades, improved understanding of the omics sciences has been crucial to the development of new treatments and screening methods for disease. ...

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appendix
Publication
April 3, 2025

Epigenetic inactivation of the autophagy–lysosomal system in appendix in Parkinson’s disease

VUGENE highlights a study on how epigenetic inactivation in the appendix may play a role in Parkinson’s disease (PD). Researchers used multiomics to explore the genes of the autophagy-lysosomal pathway ...

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Data analysis
October 18, 2024

Best Ways to Account for Batch Effects

What is a batch effects? With recent technological advancements, we’re generating high-throughput experimental data like never before. When this data comes from different experiments – with variations in timing, personnel, ...

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Data analysis
September 17, 2024

Is scRNA-seq Always Superior to Bulk RNA-seq?

Single-cell RNA sequencing (scRNA-seq) has transformed biological research by providing remarkable resolution for studying gene expression at the level of individual cells. This detailed view is invaluable for studying cellular ...

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Data analysis
July 30, 2024

Multi-omics Data Analysis Approach Enables a Better Understanding of Scientific Problems

What is multi-omics? Through simultaneous analysis of different omics datasets – genomics, transcriptomics, proteomics, metabolomics, microbiomics, and epigenomics – multi-omics offers a comprehensive view of biological systems and potential for ...

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