Metabolomics biomarkers of neurodegeneration

Client

Corewell Health is a not-for-profit health system that provides health care and coverage with an exceptional team of 65,000+ dedicated people, including more than 12,000 physicians and advanced practice providers and more than 15,500 nurses providing care and services in 21 hospitals, 300+ outpatient locations and several post-acute facilities, and Priority Health, a provider-sponsored health plan serving more than 1.3 million members.

Background

Identify small molecules that could be used for diagnostics of various neurological conditions and neurodegenerative disorders.

Solutions

  • Targeted and untargeted mass spectrometry data processing pipeline
  • Integration of metabolomics, epigenomics and other data sources
  • AI-based predictors for diagnostics and identification of novel therapeutic targets

Publications

Scientific Reports, read full article: Link
Genes, read full article: Link

Cover image credits: Anusorn / Adobe Stock